| Acquired immune deficiency syndrome (AIDS) caused by at least two types of retrovirus HIV 1 and HIV 2, collectively referred as HIV1/2. Antibody to HIV 1 core protein p24, transmembrane protein gp 41 and/or antibodies to HIV 2 transmembrane protein gp 36 are present in sera of individual infected with AIDS. HIV in Virdict 4 detects these antibodies which indicates exposure to the HIV 1/2 or both viruses. HCV is a small, enveloped single stranded RNA virus containing a linear genome with a length of about 9,600 nucleotide having positive polarity. It is the major cause of permanently transmitted non-A, non-B hepatitis. Antibodies to HCV are reported in 80% on non-A, non-B hepatitis patients. HCV infection frequently progresses to chronic liver disease. Based on phylogenetic analysis, HCV has been grouped into 6 major genotype each of which contains one or more subtype. HCV in Virdict 4 detects anti – HCV antibodies ensuring detection of all antibody isotypes viz. IgM, IgG, IgAetc. for all 6 genotypes. Syphilis is a sexually transmitted (venereal) disease caused by the spirochete Treponema pallidum. The disease can also be transmitted congenitally thereby attaining its importance in antenatal screening. After infection the host forms non-treponemal anti lipoidal antibodies to the lipoidal material released from the damaged host cells as well as Treponema specific antibodies. Serological tests for non-treponemal antibodies such as VDRL, RPR, and TRUST etc. are useful as screening tests. Tests for Treponema specific antibodies such as TPHA, FTA-ABS, rapid Treponema antibody tests are gaining importance as screening as well as confirmatory tests because they detect the presence of antibodies specific to Treponema pallidum. Syphilis in Virdict 4 is modified TPHA, which qualitatively detects the presence of IgM and IgG class of Treponema specific antibodies during syphilis infection. Blood containing hepatitis B virus (HBV) is potentially infectious. Hepatitis B surface antigen (HBsAg), earlier known as Australian antigen is among the first serological markers that circulate in blood of infected person even two to three weeks prior to appearance of clinical symptoms. The level of HBsAg is especially elevated during the symptomatic phase. Detection of HBV using HBsAg as marker to screen blood donors is essential to reduce the risk of HBV transmission through blood transfusion. HBsAg detection is also useful for screening high risk group for HBV and for differential diagnosis of Hepatitis infection. HBsAg in Virdict 4 detects presence of HBsAg in serum/plasma specimen qualitatively |
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| Virdict 4 is a Rapid Immnunochromatographic test for simultaneous detection of HBsAg and antibodies to HIV, HCV and Syphilis in human serum/plasma |
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HIV+HBSAG+HCV+SYPHILIS VIRDICT...
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