Hepatitis A is a liver disease caused by the Hepatitis A virus (HAV). It is a food and waterborne disease that is primarily transmitted by the faecal / oral route. HAV infects hepatocytes, causes elevation of liver enzymes and inflammation of the liver. The virus particles are released into the bile duct and excreted in faeces. The presence of virus in the blood is detected 2-4 weeks after infection. IgM antibodies to HAV are produced at an early stage of HAV infection and persist during the acute phase of the disease. Detection of anti HAV-IgM is confirmatory for the diagnosis of recent Hepatitis A. INSIGHT HAV-IgM, a rapid test for the detection of IgM antibodies to Hepatitis A virus in human serum or plasma enables diagnosis of the early and acute stage of infection |
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