After treatment, in the recovery phase following acute Hepatitis B infection, HBeAg becomes negative. Antibodies to the ‘e’ antigen (HBeAb) normally appears a few weeks after HBeAg is no longer detectable. The presence of HBeAb generally indicates that the patient is recovering from the acute stage of the illness. INSIGHT HBeAb detects the presence of HBeAb in human serum and helps determine whether the HBV infection is resolved. Presence of HBeAb suggests low or missing infectivity and serves as a measure of patient infectivity. In monitoring the cause of accute and chronic HBV infections, the occurence of HBeAb and disappearance of HBeAg are of prognostic value. |
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