The hepatitis B ‘e’ antigen (HBeAg), has been found in the hepatocytes during proliferation of the hepatitis B virus. Its detection is associated with pronounced viral infection and infectivity. After treatment, in the recovery phase following acute Hepatitis B infection, HBeAg becomes negative. HBeAg is generally detectable at the same time as HBsAg and disappears before HBsAg disappears. The presence of HBeAg in chronic infection indicates that HBV is actively reproducing and there is a high possibility of liver damage. In acute infection, HBeAg is generally present in trace amounts and its disappearance indicates accute or chronic Hepatitis B which is in the process of healing. INSIGHT HBeAg detects the presence of HBeAg in human serum, thereby giving an assessment of the infectivity and the patient’s status.
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