α Amylase is secreted by the pancreas into the duodenum where it aids the catabolism of carbohydrates to simple sugars. Damage to the pancreas or obstruction to the pancreatic duct causes the enzyme to enter the blood stream. Elevated levels are found in acute pancreatitis, perforated / penetrating peptic ulcers, paraotitis (mumps). Patients with chronic pancreatic disorders having pancreatic cell destruction do not have high levels as less amylase is produced by the pancreas.
